Peptider, som forhøjer sekretion og/eller eksprimering af mindst én mave-tarm-mucin og/eller inducerer forhøjelsen af populationen af mucus-cellerne eller af Paneth-celler

The invention relates to a polypeptide including or consisting of SEQ ID NO: 1, or a sequence at least 80% identical to SEQ ID NO: 1, or a sequence of at least 4 consecutive amino acids included in SEQ ID NO: 1, wherein said polypeptide has at least one effect selected from: inducing the expression...

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Bibliographische Detailangaben
Hauptverfasser: CLAUSTRE, Jean, HENRY, Gwénaele, LEONIL, Joelle, PLAISANCIÉ, Pascale, JOURDAN, Gérard, MOLLE, Daniel, PAQUET, Armelle, MADEC, Marie-Noelle, ESTIENNE, Monique, GOGLY, Rachel
Format: Patent
Sprache:dan
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Zusammenfassung:The invention relates to a polypeptide including or consisting of SEQ ID NO: 1, or a sequence at least 80% identical to SEQ ID NO: 1, or a sequence of at least 4 consecutive amino acids included in SEQ ID NO: 1, wherein said polypeptide has at least one effect selected from: inducing the expression and/or the secretion of at least one gastrointestinal mucin; and inducing the expression and/or the secretion of at least one intestinal defense molecule expressed by Paneth cells; and inducing an increase in the population of mucus cells and/or in the population of Paneth cells, with the proviso that the polypeptide does not include the SEQ ID NO: 2 sequence.