Cyklisk pyrimidin-4-carboxamider, som CCR2-receptor-antagonister til behandling af inflammation, astma og COPD

Cyklisk pyrimidin-4-carboxamider, som CCR2-receptor-antagonister til behandling af inflammation, astma og COPD

The present invention relates to a process for the production of novel antagonists for CCR2 (CC chemokine receptor 2) of formula (I) from 6-Chloro-pyrimidine-methanone intermediates. Formula (I): Specifically claimed 6-chloropyrimidine-methanone intermediates are:

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Bibliographische Detailangaben
Hauptverfasser: HOENKE, CHRISTOPH, EBEL, HEINER, TRIESELMANN, THOMAS, SCHEUERER, STEFAN, FRATTINI, SARA, HOBBIE, SILKE (MARIE KATRIN), TIELMANN, PATRICK, BUETTNER, FRANK, GIOVANNINI, RICCARDO
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to a process for the production of novel antagonists for CCR2 (CC chemokine receptor 2) of formula (I) from 6-Chloro-pyrimidine-methanone intermediates. Formula (I): Specifically claimed 6-chloropyrimidine-methanone intermediates are: