SUBSTITUEREDE PHENYLACETYLENER DERES FREMSTILLING OG ANVENDELSE

SUBSTITUEREDE PHENYLACETYLENER DERES FREMSTILLING OG ANVENDELSE

The compounds of formula I, in which R is H, alkyl, aralkyl or diaralkyl, R is H or a halogen and R is H, alkyl, aralkyl, aryl, aryloxy, benzoyl or 2-thienocarbonyl, R and R not being simultaneously H, are obtained by halogenation of a ketone of formula II, followed by dehydrohalogenation of the int...

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Bibliographische Detailangaben
Hauptverfasser: PALOSI E, KORBONITS D, SZEBENI R, KISS P, MOLNAR E, HEJA G, GOENCZI C
Format: Patent
Sprache:dan
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:The compounds of formula I, in which R is H, alkyl, aralkyl or diaralkyl, R is H or a halogen and R is H, alkyl, aralkyl, aryl, aryloxy, benzoyl or 2-thienocarbonyl, R and R not being simultaneously H, are obtained by halogenation of a ketone of formula II, followed by dehydrohalogenation of the intermediate halogenated derivative of formula III by means of a strong base. The compounds of formula I are useful as intermediates for the preparation of pharmaceutically active compounds.