THIAZOLOPYRIDIN-2-YLOXY-PHENYL OG THIAZOLOPYRAZIN-2-YLOXY-PHENYL-AMINER SOM MODULATORER AF LEUKOTRIEN-A4-HYDROLASE

Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, an...

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Hauptverfasser:	DENG, XIAOHU, MANI, NEELAKANDHA, S, FOURINE, ANNE, M, GOMEZ, LAURENT, LANDRY-BAYLE, ADRIENNE, M, WICKBOLDT, ALVAH, T, GRICE, CHERYL, A, CHROVIAN, CHRISTA, C, SEPASSI, KIA, LOCHNER, SUSANNE, LEE-DUTRA, ALICE, CHEUNG, EUGENE, Y, WIENER, JOHN, J. M, BROGGINI, DIEGO, ZINSER, HARTMUT, SANTILLAN, ALEJANDRO, LIANG, JIMMY, T, BACANI, GENESIS, M, SAPPEY, KATHLEEN, C, TANIS, VIRGINIA, M, KEARNEY, AARON, M
Format:	Patent
Sprache:	dan
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:	Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity.