Pyrimidinderivater anvendt som PI-3-kinasehæmmere

Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; in the prophylaxis or treatment of proliferative diseases characterized by the abnormal acti...

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Hauptverfasser:	PECCHI, SABINA, KNAPP, MARK, ZHANG, YANCHEN, PFISTER, KEITH, BURGER, MATTHEW, BARTULIS, SARAH, XIN, XIAHUA, WIESMANN, MARION, MERITT, HANNE, WAGMAN, ALLAN, POON, DANIEL, NI, ZHI-JIE, ATALLAH, GORDANA, SMITH, AARON, FANTL, WENDY, LOUIE, ALICIA, FRAZIER, KELLY, VERHAGEN, JOELLE, IWANOWICZ, EDWIN, BARSANTI, PAUL, PICK, TERESA, HENDRICKSON, THOMAS, VOLIVA, CHARLES, NG, SIMON
Format:	Patent
Sprache:	dan
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.