Modulation af granulosa-celleapoptose

The present invention relates to a culture medium for an oocyte and/or an embryo, the medium including either or both of (i) GDF-9 or a variant thereof; and (ii) an agent that increases the activity of a GDF-9 dependent signalling pathway in one or more of an oocyte, a cumulus cell associated with a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Hussein, Tamer, Gilchrist, Robert Bruce, Thompson, Jeremy
Format:	Patent
Sprache:	dan
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a culture medium for an oocyte and/or an embryo, the medium including either or both of (i) GDF-9 or a variant thereof; and (ii) an agent that increases the activity of a GDF-9 dependent signalling pathway in one or more of an oocyte, a cumulus cell associated with an oocyte, and an embryo; and to methods using such culture medium.