PEGYLERET AMYLOID BETA FAB

A method to treat conditions associated with A² peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human A² peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached...

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Bibliographische Detailangaben
Hauptverfasser: KUCHIBHOTLA, UMA, CHOW, CHI-KIN, DEMATTOS, RONALD, BRADLEY, LU, JIRONG, BUMOL, THOMAS, FRANK, BALES, KELLY, RENEE, MCDONNELL, PETER, COLON, HANSEN, RYAN, JOHN
Format: Patent
Sprache:dan
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Zusammenfassung:A method to treat conditions associated with A² peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human A² peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached to a polyethylene glycol (PEG) molecule.