SAMMENSÆTNINGER, DER ER EGNET TIL BEHANDLING AF KOLLAGENBETINGEDE SYGDOMME

A drug product comprising a combination of highly purified collagenase I and collagenase II from Colostridium histolyticum is disclosed. The drug product includes collagenase I and collagenase II in a ratio of about 1 to 1, with a purity of greater than at least 95%. The invention further disclosed...

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Hauptverfasser: SABATINO, Gregory, L, BASSETT, Phillip, J, YU, Bo, DEL TITO, JR., Benjamin, J, HITCHCOCK, Antony, G, THARIA, Hazel, A, WEGMAN, Thomas L
Format: Patent
Sprache:dan
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Zusammenfassung:A drug product comprising a combination of highly purified collagenase I and collagenase II from Colostridium histolyticum is disclosed. The drug product includes collagenase I and collagenase II in a ratio of about 1 to 1, with a purity of greater than at least 95%. The invention further disclosed improved fermentation and purification processes for preparing the said drug product.