Fremgangsmåde til masseproduktion af en immunoglobulin-Fc-region uden start-methioninrester

Disclosed is a method for the mass production of a monomeric or dimeric immunoglobulin Fc region, free of initial methionine residues, using a recombinant expression vector comprising a nucleotide sequence coding for a recombinant immunoglobulin Fc region comprising an immunoglobulin Fc region linke...

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Bibliographische Detailangaben
Hauptverfasser: LEE, GWAN-SUN, JUNG, SUNG YOUB, KIM, JIN SUN, SHIN, JIN HWAN, KWON, SEANG, SONG, DAE HAE
Format: Patent
Sprache:dan
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Zusammenfassung:Disclosed is a method for the mass production of a monomeric or dimeric immunoglobulin Fc region, free of initial methionine residues, using a recombinant expression vector comprising a nucleotide sequence coding for a recombinant immunoglobulin Fc region comprising an immunoglobulin Fc region linked at the N-terminus thereof to an immunoglobulin Fc region via a peptide bond.