N-PHENYL-2-PYRIMIDIN-AMINDERIVATER OG FREMGANGSMÅDE TIL FREMSTILLINGEN DERAF

The present invention relates to a novel N-phenyl-2-pyrimidine-amine derivative represented by the above formula (1) and its salt showing a superior effect on cancer in warm-blooded animals, such as lung cancer, gastric cancer, colon cancer, pancreatic cancer, hepatoma, prostatic cancer, breast canc...

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Bibliographische Detailangaben
Hauptverfasser: LEE, SUN-AHE, KIM, DONG-YEON, KIM, HONG-YOUB, KIM, YONG-SEOK, CHO, DAE-JIN, LEE, GONG-YEAL, WOO, SEOK-HUN, HAN, BYOUNGOL
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Sprache:dan
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Beschreibung
Zusammenfassung:The present invention relates to a novel N-phenyl-2-pyrimidine-amine derivative represented by the above formula (1) and its salt showing a superior effect on cancer in warm-blooded animals, such as lung cancer, gastric cancer, colon cancer, pancreatic cancer, hepatoma, prostatic cancer, breast cancer, chronic or acute leukemia, hematologic malignancy, encephalophyma, bladder cancer, rectal cancer, cervical cancer, lymphoma, etc. The present invention also relates to a process for preparing the compound, and to a pharmaceutical composition for the treatment of the above various diseases, which comprises an effective amount of the compound as an active ingredient together with pharmaceutically acceptable inert carriers.