Inhibitorer af cytosol-phospholipase A2

This invention provides substituted indole compounds of the general formula: (I) and pharmaceutically acceptable salt forms thereof, and methods for using the compounds as inhibitors of the activity of various phospholipase enzymes, particularly phospholipase A2 enzymes, and for the medical treatmen...

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Bibliographische Detailangaben
Hauptverfasser:	THAKKER, PARESH, TAM, STEVE, YIK-KAI, CHEN, LIHREN, MCKEW, JOHN, CAEDMON, SUM, FUK-WAH, LEE, KATHERINE, LIN, BEHNKE, MARK, LEO, CLARK, JAMES, DONALD, HU, BAIHUA
Format:	Patent
Sprache:	dan
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention provides substituted indole compounds of the general formula: (I) and pharmaceutically acceptable salt forms thereof, and methods for using the compounds as inhibitors of the activity of various phospholipase enzymes, particularly phospholipase A2 enzymes, and for the medical treatment, prevention and inhibition of pain and inflammation.