Fremgangsmåde til kromatografi med svag opdeling

This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bin...

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Hauptverfasser: BROWN, Paul, COFFMAN, Jon, KELLEY, Brian D, SWITZER, Mary Beth, ISKRA, Tim, SUN, Shujun, BOOTH, James, Edward, YU, Tianning, VUNNUM, Suresh, GODAVARTI, Ranganathan
Format: Patent
Sprache:dan
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Zusammenfassung:This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bind least 1 mg of product per mL of medium, or alternatively, defined by a partition coefficient of at least 0.1.