(S)-(-)-1-(4-fluorisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazinhydrochloriddihydrat

(S)-(-)-1-(4-fluorisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazinhydrochloriddihydrat

The present invention is directed to (S)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate, to a method producing the dihydrate, and to a drug composition containing the dihydrate. The compound of the present invention has less hygroscopicity as compared wi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HIDAKA, HIROYOSHI, ODA, TOSHIAKI, OHSHIMA, TAKESHI, SHIRATSUCHI, MASAMI, ONOGI, KAZUHIRO
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention is directed to (S)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate, to a method producing the dihydrate, and to a drug composition containing the dihydrate. The compound of the present invention has less hygroscopicity as compared with (S)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride anhydrous crystals and thus, exhibits excellent chemical stability.