Self-emulsifying systems for cannabinoids

The present invention relates to an orally dissolvable or chewable tableted powder formulation. The formulation comprising one or more carrier systems comprising one or more liquid or solid self-emulsifying systems loaded with cannabinoids in an amount of at least 10% by weight of the tableted powde...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sanne Skov Jensen, Rasmus Blaaholm, Simon Laursen, Gitte Nykjær Nikolajsen, Dorte Boesen
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to an orally dissolvable or chewable tableted powder formulation. The formulation comprising one or more carrier systems comprising one or more liquid or solid self-emulsifying systems loaded with cannabinoids in an amount of at least 10% by weight of the tableted powder formulation; the one or more self-emulsifying systems including: i) at least one or more surfactants, one or more lipids and one or more isolated or synthetic cannabinoids when the self-emulsifying system is a liquid self-emulsifying system, and ii) at least one or more surfactants, one or more waxes and one or more isolated or synthetic cannabinoids when the self-emulsifying system is a solid self-emulsifying system. The formulation further including one or more water-soluble agents in an amount of 20-80% by weight of the tableted powder formulation and one or more flavors, wherein the one or more self-emulsifying systems is stable at a pH of about 1-4 and operable to gastrointestinal tract delivery of the one or more cannabinoids upon release of the one or more carrier systems in the oral cavity.