ANTI-P-SELECTIN-ANTISTOFFER

This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suff...

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Hauptverfasser: JANSEN-MOLENAAR, MIRANDA, PARREN, PAUL, GRAUS, YVO, HIMBER, JACQUES, KLING, DOROTHEE, STREIN, PAMELA, STUBENRAUCH, KAY-GUNNAR, REBERS, FRANK, STEINER, BEAT, STERN, ANNE, VAN VUGT, MARTINE, KOPETZKY, ERHARD, VAN DE WINKEL, JAN
Format: Patent
Sprache:dan
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Zusammenfassung:This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).