Biokatalytisk fremstilling af (meth)acyrlylcholin eller 2-(N,N-dimethylamino)ethyl (meth)acrylat

A biocatalytic method for the synthesis of 2-(N,N-dimethyl amino)ethanol and/or choline esters of acrylic acid and/or methacrylic acid comprising reacting 2-(N,N-dimethylamino)ethanol and/or choline with acrylyl-CoA and/or methacrylyl-coA in the presence of a biocatalyst with choline acetyltransfera...

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Bibliographische Detailangaben
Hauptverfasser: HUGHES, JONATHAN, SYMES, KENNETH, CHARLES
Format: Patent
Sprache:dan
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Beschreibung
Zusammenfassung:A biocatalytic method for the synthesis of 2-(N,N-dimethyl amino)ethanol and/or choline esters of acrylic acid and/or methacrylic acid comprising reacting 2-(N,N-dimethylamino)ethanol and/or choline with acrylyl-CoA and/or methacrylyl-coA in the presence of a biocatalyst with choline acetyltransferase activity. The acrylyl-CoA and/or the methacrylyl CoA is formed by the reaction of acrylate and/or methacrylate with coenzyme A in the presence of ATP and a biocatalyst with S-acetyl coenzyme A synthetase activity.