INFUSIONS- OG INJEKTIONSOPLOESNINGER AF QUINOLONCARBOXYLSYRER OG FREMGANGSMAADE TIL DERES FREMSTILLING

INFUSIONS- OG INJEKTIONSOPLOESNINGER AF QUINOLONCARBOXYLSYRER OG FREMGANGSMAADE TIL DERES FREMSTILLING

Improvement in the parenteral administration of a carboxylic acid of the formula (I) or (II) in which X is N, C-H or C-F, Z is O or Ch2, R1 is hydrogen, methyl, ethyl or beta -hydroxyethyl, R2 is cyclopropyl, 2-fluoroethyl or ethyl, R3 is hydrogen or methyl, and R4 is H or methyl, is achieved throug...

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Bibliographische Detailangaben
Hauptverfasser: NAIK, ARUNDEV HARIBHAI, VOEGE, HERBERT, GROHE, KLAUS, SCHLUETER, GERHARD
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Improvement in the parenteral administration of a carboxylic acid of the formula (I) or (II) in which X is N, C-H or C-F, Z is O or Ch2, R1 is hydrogen, methyl, ethyl or beta -hydroxyethyl, R2 is cyclopropyl, 2-fluoroethyl or ethyl, R3 is hydrogen or methyl, and R4 is H or methyl, is achieved through the administration of the basic salt of the acid (I, II). Surprisingly the basic salts are suitable and stable.