ANALOGIFREMGANGSMAADE TIL FREMSTILLING AF 4-SUBSTITUEREDE QUINAZOLINER

ANALOGIFREMGANGSMAADE TIL FREMSTILLING AF 4-SUBSTITUEREDE QUINAZOLINER

Compounds of the formula wherein R1 is hydrogen, alkyl of 1 to 4 carbon atoms or trifluoromethyl; R2, R3 and R4 are each independently hydrogen, methyl or ethyl; R5 is hydrogen, alkyl of 1 to 8 carbon atoms, phenyl-(alkyl of 1 to 8 carbon atoms), cycloalkyl of 3 to 7 carbon atoms, (alkoxy of 1 to 4...

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Bibliographische Detailangaben
Hauptverfasser: SCHROMM, KURT, TRAUNECKER, WERNER, REICHL, RICHARD, MENTRUP, ANTON, RENTH, ERNST-OTTO
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds of the formula wherein R1 is hydrogen, alkyl of 1 to 4 carbon atoms or trifluoromethyl; R2, R3 and R4 are each independently hydrogen, methyl or ethyl; R5 is hydrogen, alkyl of 1 to 8 carbon atoms, phenyl-(alkyl of 1 to 8 carbon atoms), cycloalkyl of 3 to 7 carbon atoms, (alkoxy of 1 to 4 carbon atoms) carbonyl-methyl, phenyl, substituted phenyl, naphthyl or substituted naphthyl; or R4 and R5, together with each other, are alkylene of 4 to 5 carbon atoms, optionally interrupted by -O- or -NR6-, where R6 is alkyl of 1 to 4 carbon atoms; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as cardiotonics.