2,4,6-TRIIOD-ISOPHTHALSYREDERIVATER, FREMGANGSMAADE TIL FREMSTILLING DERAF OG ROENTGENKONTRASTMIDDEL INDEHOLDENDE DISSE FORBINDELSER

Novel, radio-opaque compounds comprising water-soluble bis-[N-{3,5-bis-(hydroxyalkylaminocarbonyl)-2,4,6-triiodo-phenyl}-N-( alpha -hydroxyacyl)-amino]-alkanes are disclosed for use as X-ray contrast agents. These compounds are relatively simple to synthesize, possess low toxicity and have good stab...

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Bibliographische Detailangaben
Hauptverfasser: ERNST FELDER, DAVIDE PITRE
Format: Patent
Sprache:dan
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Zusammenfassung:Novel, radio-opaque compounds comprising water-soluble bis-[N-{3,5-bis-(hydroxyalkylaminocarbonyl)-2,4,6-triiodo-phenyl}-N-( alpha -hydroxyacyl)-amino]-alkanes are disclosed for use as X-ray contrast agents. These compounds are relatively simple to synthesize, possess low toxicity and have good stability as well as resistance to hydrolysis. Methods for preparation and use of the compounds are also disclosed.