ANALOGIFREMGANGSMAADE TIL FREMSTILLING AF 2,4-(1H,3H)-QUINAZOLINDIONDERIVATER ELLER FARMACEUTISK ACCEPTABLE SYREADDITIONSSALTE DERAF

ANALOGIFREMGANGSMAADE TIL FREMSTILLING AF 2,4-(1H,3H)-QUINAZOLINDIONDERIVATER ELLER FARMACEUTISK ACCEPTABLE SYREADDITIONSSALTE DERAF

Phenylpiperazine derivatives of the formula:wherein R, is a hydrogen atom or a straight- or branched-chain saturated or unsaturated alkyl group having 1 to 8 carbon atoms which may be substituted at any position by a hydroxyl group, a carboxyl group, a lower alkoxycarbonyl group or an oxo group; and...

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Bibliographische Detailangaben
Hauptverfasser: TAKAGI, MITIRO, MATSUNAGA, ISAO, NABATA, HIROYUKI, NAGANO, HIROYUKI, UCHIDA, YASUMI, KUBODERA, NOBORU, OHBA, YASUHIRO, SAKAI, KAZUSHIGE, HATA, SHUN-ISHI
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Phenylpiperazine derivatives of the formula:wherein R, is a hydrogen atom or a straight- or branched-chain saturated or unsaturated alkyl group having 1 to 8 carbon atoms which may be substituted at any position by a hydroxyl group, a carboxyl group, a lower alkoxycarbonyl group or an oxo group; and R2 is a hydrogen atom, a halogen atom, a lower alkyl group or a sulfamoyl group; and a process for producing the same are disclosed. The derivatives of the formula have alpha blocking and serotonin antagonizing activities and are useful as a drug.