Optimerede Fc-varianter og fremgangsmåder til generering heraf

The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.

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Bibliographische Detailangaben
Hauptverfasser: LAZAR, GREGORY, ALAN, DESJARLAIS, JOHN, RUDOLPH, KARKI, SHER, BAHADUR, DOBERSTEIN, STEPHEN, KOHL, CHIRINO, ARTHUR, J, HAYES, ROBERT, J, VAFA, OMID, DANG, WEI
Format: Patent
Sprache:dan
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Beschreibung
Zusammenfassung:The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.