Hidtil ukendte pleuromultilinderivater

Pleuromutilin compounds of the formula (A) & (B) are of use in anti-bacterial therapy. in which: R 1 is optionally substituted C (1-6) alkyl or C (3-6) cycloalkyl or optionally substituted heterocyclyl; R 2 is vinyl or ethyl; R 3 is H, OH or F, and R 4 is H, or R 3 is H and R 4 is F, and R 5 and...

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Hauptverfasser: SHEPPARD, ROBERT JOHN, JARVEST, RICHARD LEWIS, FORREST, ANDREW KEITH, ELDER, JOHN STEPHEN
Format: Patent
Sprache:dan
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Zusammenfassung:Pleuromutilin compounds of the formula (A) & (B) are of use in anti-bacterial therapy. in which: R 1 is optionally substituted C (1-6) alkyl or C (3-6) cycloalkyl or optionally substituted heterocyclyl; R 2 is vinyl or ethyl; R 3 is H, OH or F, and R 4 is H, or R 3 is H and R 4 is F, and R 5 and R 6 together form an oxo group; or R 3 and R 4 is each H, R 5 is OH or H and R 6 is H, or R 5 is H and R 6 is OH or H.