Anvendelse af muteret VEGF til antiangiogen terapi

The invention relates to the application of oligonucleotide and polypeptide sequences of molecules belonging to the vascular permeability factor (VPF) family, their receptors and co-receptors and to their modifications in active immunotherapy against pathological entities whose course is associated...

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Hauptverfasser: FERNANDEZ MOLINA, LUIS, ENRIQUE, GAVILONDO COWLEY, JORGE, VICTOR, LOPEZ OCEJO, OMAR, BEQUET ROMERO, MONICA, SILVA RODRIGUEZ, RICARDO, DE LA CARIDAD, GALBAN RODRIGUEZ, ERNESTO, VAZQUEZ BLOMQUIST, DANIA, MARCIA, MUSACHIO LASA, ALEXIS, ACEVEDO CASTRO, BORIS, ERNESTO
Format: Patent
Sprache:dan
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Zusammenfassung:The invention relates to the application of oligonucleotide and polypeptide sequences of molecules belonging to the vascular permeability factor (VPF) family, their receptors and co-receptors and to their modifications in active immunotherapy against pathological entities whose course is associated with an increase in vasculature. Said procedures can be used, inter alia, in monotherapy or combined therapy for the treatment of cancer and its metastasis, acute and chronic inflammatory processes, infectious diseases, autoimmune diseases, diabetic and infant retinopathy, rejection of transplanted organs, macular degeneration, neovascular glaucoma, hemangioma and angiofibroma.