ANALOGIFREMGANGSMAADE TIL FREMSTILLING AF ERGOLEN- ELLER ERGOLIN-DERIVATER ELLER SYREADDITIONSSALTE DERAF

ANALOGIFREMGANGSMAADE TIL FREMSTILLING AF ERGOLEN- ELLER ERGOLIN-DERIVATER ELLER SYREADDITIONSSALTE DERAF

Novel ergoline compounds of the following formula are described:wherein R1 is ethyl, n-propyl, or allyl; Y is O, S, SO, or SO2; X is hydrogen, chloro, or bromo; the dotted line represents the optional presence of a double bond; and the pharmaceutically-acceptable acid addition salts thereof. The com...

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Bibliographische Detailangaben
Hauptverfasser: BACH, NICHOLAS JAMES, KORNFELD, EDMUND CARL
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Novel ergoline compounds of the following formula are described:wherein R1 is ethyl, n-propyl, or allyl; Y is O, S, SO, or SO2; X is hydrogen, chloro, or bromo; the dotted line represents the optional presence of a double bond; and the pharmaceutically-acceptable acid addition salts thereof. The compounds are useful to inhibit prolactin secretion or to treat Parkinson's syndrome.