Fremgangsmåde til identifikation af mikroorganismer ved hjælp af massespektrometri

Identifying microorganisms (A) by mass spectrometry (MS). Identifying microorganisms (A) by mass spectrometry (MS) comprises: (1) establishing a database (DB) that contains: (a) synthetic reference spectra (REFs) of known (A), produced by compiling a number of specific signals (S) for each (A), wher...

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Bibliographische Detailangaben
Hauptverfasser: KALLOW, WIBKE, ERHARD, MARCEL, DIECKMANN, RALF, SAUERMANN, STEFAN
Format: Patent
Sprache:dan
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Zusammenfassung:Identifying microorganisms (A) by mass spectrometry (MS). Identifying microorganisms (A) by mass spectrometry (MS) comprises: (1) establishing a database (DB) that contains: (a) synthetic reference spectra (REFs) of known (A), produced by compiling a number of specific signals (S) for each (A), where this number is fewer than the total number of signals in the natural reference spectrum (REFn); and (b) difference spectra (DIF) formed from any two REFs for known (A); (2) performing similarity analysis of a sample mass spectrum (SAM) of the organism being identified with REFs in DB; and (3) performing similarity analysis of SAM with at least some of the DIF in DB. An Independent claim is also included for a database for the process.