FREMGANGSMADE TIL FREMSTILLING AF TRANS-DECALINDERIVATER

A process for the preparation of trans-decahydronaphthalene compounds of Formula I I wherein X is lower alkyl, -(CH2)3-Z-R2, -(CH2)3COOR4, or -(CH2)3CN; Y and Z are ketalized carbonyl or free, esterified, or etherified hydroxymethylene; U is halogen; R1, R2, and R3 are lower alkyl; and R4 is alkyl;...

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Bibliographische Detailangaben
Hauptverfasser:	WIECHERT R, SAUER G, EDER U, HAFFER G, NEEF G
Format:	Patent
Sprache:	dan
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	A process for the preparation of trans-decahydronaphthalene compounds of Formula I I wherein X is lower alkyl, -(CH2)3-Z-R2, -(CH2)3COOR4, or -(CH2)3CN; Y and Z are ketalized carbonyl or free, esterified, or etherified hydroxymethylene; U is halogen; R1, R2, and R3 are lower alkyl; and R4 is alkyl; WHEREIN AN OCTAHYDRONAPHTHALENE COMPOUND OF Formula II II is converted, in the presence of bases, by reaction of a trialkyl chlorosilane of the formula (R5)3Si-Cl WHEREIN THE R5 each are lower alkyl group, to a hexahydronaphthalene compound of the formula The hexahydronaphthalene compound is hydrogenated, in an inert solvent with hydrogen in the presence of a platinum-, palladium-, or rhodium-containing hydrogenation catalyst, to an octahydronaphthalene compound of the formula and a vinyl ketone of the formula XCOCH=CH2 is added to the thus-obtained octahydronaphthalene compound in an inert solvent in the presence of a Lewis acid.