ANALOGIFREMGANGSMADE TIL FREMSTILLING AF BENZENSULFONAMIDOPYRIMIDINER

1377793 Benzenesulphonamido-pyrimidines FARBWERKE HOECHST AG 17 Feb 1972 [17 Feb 1971] 7398/72 Heading C2C Novel compounds (I) (including salts thereof) where X is H, Cl, Br, Me or MeO, Y signifies -CHMeCH 2 - or -CH 2 -CH 2 -; R is H or together with Y is a 3 or 4 C bridge, R1 is alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, alkoxy, cycloalkoxy, alkoxyalkyl, alkoxyalkoxy, alkylmercapto or alkylmercaptoalkyl, R11 is H or alkyl and R1 and R11 together represent C 3 to C 5 alkylene, are made by standard methods. The preparations of 4-(#-quinoline-8-carboxamido - ethyl) - benzenesulphochloride and of compounds VIII are also described. Pharmaceutical preparations showing hypoglycemic action contain (I) as active ingredient; administration is, e.g. orally.