DK129124C

1,234,359. Isonipecotic acid derivative. JANSSEN PHARMACEUTICA N.V. 31 Oct., 1969 [4 Nov., 1968], No. 53573/69. Heading C2C. The novel compound, 1 - (3 - cyano - 3,3- diphenylpropyl) - 4 - phenylisonipecotic acid, and its pharmaceutically acceptable acid addition salts, are prepared by hydrolysing a C 1-7 alkyl ester of said acid, and, if desired, converting the resulting acid into a pharmaceutically acceptable acid addition salt thereof. Pharmaceutical compositions having antidiarrheal and analgesic activity comprise the novel compound, or a pharmaceutically acceptable acid addition salt thereof, together with a pharmaceutical carrier. The compositions may be administered orally or parenterally, e.g. in the form of tablets, capsules, powders, suspensions, elixirs and solutions. Reference has been directed by the Comptroller to Specification 843,319.