Fremgangsmåde til fremstilling af et octapeptidderivat eller syreadditionssalte deraf

A polypeptide of the general formula (also known as desamino1-Arg8-vasopressin) and its acid addition salts is prepared by oxidizing a linear peptide of the formula the linear peptide in turn being prepared by reacting a hexapeptide of the formula with a reactive derivative of a free acid of the formula in which R1 is a sulphhydryl protecting group and R11 a guanido protecting group, to give an appropriately protected linear octapeptide and removing the protecting groups therefrom. S - Benzyl - b - mercaptopropionyl - L - tyrosyl-L-phenylalanine hydrazide is prepared missing texts S-benzyl-b -mercaptopropionic acid missing texts 2,4,5 - trichlorophenyl ester and S - missing texts mercaptopropionyl - L - tyrosyl - missing texts alanine methyl ester. O,N - Dicarbobenzoxy - L missing texts phenyl - alanine methyl ester missing texts L-phenylalanine methyl missing texts benzoxy - L - tyrosine - missing texts ester. Pharmaceutical missing texts pounds of the missing texts carrier. The missing texts suitable for missing texts nasal missing texts invention missing texts