Kemisk fremgangsmåde til fremstilling af 2-hydroxy-6-trifluormethylpyridin

Kemisk fremgangsmåde til fremstilling af 2-hydroxy-6-trifluormethylpyridin

A process for the preparation of 2-hydroxy-6-trifluoromethylpyridine which comprises reacting 2-fluoro-6-trifluomethylpyridine or a mixture of 2-fluoro-6-trifluoromethylpyridine and 2-chloro-6-trifluoromethylpyridine with an alkali metal hydroxide at a temperature of from 50 DEG C. to 160 DEG C. and...

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Bibliographische Detailangaben
Hauptverfasser: SEIDEL, ERWIN, MICHAEL, JONES, RAYMOND, VINCENT, HEAVON, HUNT, JOHN, DESMOND, WHITTON, ALAN, JOHN, WHITE, JENNIFER, ANN, FUNG, ALEXANDER, STEWART, ALASTAIR, IAIN, CURRIE, FRIESE, DAVID
Format: Patent
Sprache:dan
Schlagworte:
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:A process for the preparation of 2-hydroxy-6-trifluoromethylpyridine which comprises reacting 2-fluoro-6-trifluomethylpyridine or a mixture of 2-fluoro-6-trifluoromethylpyridine and 2-chloro-6-trifluoromethylpyridine with an alkali metal hydroxide at a temperature of from 50 DEG C. to 160 DEG C. and acidifying the product so formed.