Hydrogelpræparater til controlled release-administration af vækstfaktorer

Compositions and methods are disclosed for the controlled release delivery of polypeptide growth factors. The compositions of the invention are hydrogels which comprise: a polypeptide growth factor having at least one region of positive charge; a physiologically acceptable water-miscible anionic pol...

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Bibliographische Detailangaben
Hauptverfasser: YANG, BING, PROTTER, ANDREW, A, JENNINGS, ROBERT, N., JR, WANG, YUANG, JOHN
Format: Patent
Sprache:dan
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Zusammenfassung:Compositions and methods are disclosed for the controlled release delivery of polypeptide growth factors. The compositions of the invention are hydrogels which comprise: a polypeptide growth factor having at least one region of positive charge; a physiologically acceptable water-miscible anionic polymer; a physiologically acceptable non-ionic polymeric viscosity controlling agent; and water.