Substituerede [2-(1-piperazinyl)ethoxy]methylforbindelser

PCT No. PCT/BE97/00038 Sec. 371 Date Oct. 9, 1998 Sec. 102(e) Date Oct. 9, 1998 PCT Filed Mar. 28, 1997 PCT Pub. No. WO97/37982 PCT Pub. Date Oct. 16, 1997Novel substituted [2-(1-piperazinyl)ethoxy]methyl compounds. The present invention related to novel substituted [2-(1-piperazinyl)-ethoxy]methyl compounds of formula in which R1 represents a -CONH2, -CN, -COOH, -COOM or -COOR3 group, M being an alkali metal and R3 being an alkyl radical having from 1 to 4 carbon atoms; and R2 represents a hydrogen atom or a group -COR4 or -R5, where R4 is chosen from the groups -OR6 or -R7, in which R5 represents an allyl or alkylaryl radical, R6 represents a linear or branched alkyl radical having from 1 to 4 carbon atoms, a haloalkyl, alkylaryl, alkylnitroaryl or alkylhaloaryl radical, and R7 represents a haloalkyl radical, to a process for the preparation of these compounds, and to their use for the preparation of compounds which are themselves valuable intermediates for the preparation of 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid or 2-[2-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]-acetic acid and/or pharmaceutically acceptable salts thereof.