Pyrrolopyrrolon derivater som inhibitorer for neutrofil elastase

PCT No. PCT/EP97/01530 Sec. 371 Date Sep. 25, 1998 Sec. 102(e) Date Sep. 25, 1998 PCT Filed Mar. 26, 1997 PCT Pub. No. WO97/36903 PCT Pub. Date Oct. 9, 1997There are described according to the invention compounds of formula (I) (relative stereochemistry indicated), wherein R1, R2, R3 and X are as de...

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Hauptverfasser: FINCH, HARRY, GLAXO WELLCOME PLC, SHAH, PRITOM, GLAXO WELLCOME PLC, SMITH, ROBIN ANDREW, GLAXO WELLCOME PLC, MACDONALD, SIMON JOHN FAWCETT, GLAXO WELLCOME PLC, HARRISON, LEE ANDREW, GLAXO WELLCOME PLC, DOWLE, MICHAEL DENNIS, GLAXO WELLCOME PLC, JOHNSON, MARTIN REDPATH, GLAXO WELLCOME PLC, INGLIS, GRAHAM GEORGE ADAM, GLAXO WELLCOME PLC
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Zusammenfassung:PCT No. PCT/EP97/01530 Sec. 371 Date Sep. 25, 1998 Sec. 102(e) Date Sep. 25, 1998 PCT Filed Mar. 26, 1997 PCT Pub. No. WO97/36903 PCT Pub. Date Oct. 9, 1997There are described according to the invention compounds of formula (I) (relative stereochemistry indicated), wherein R1, R2, R3 and X are as defined in the specification, together with processes for preparing them, compositions containing them and their use as pharmaceuticals. Compounds of formula (I) are indicated inter alia for the treatment of chronic bronchitis.