Para-substituerede phenylpropansyrederivater som integrinantagonister

The present invention relates to a class of compounds represented by Formula Ior a pharmaceutically acceptable salt thereof, pharmaceutical composition comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the alphavbeta3 integrin.

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Bibliographische Detailangaben
Hauptverfasser: CHEN, BARBARA, B, MALECHA, JAMES, W, ROGERS, THOMAS, E, RUMINSKI, PETER, G, CHEN, HELEN, Y, GESICKI, GLEN, J, HAACK, RICHARD, A, RUSSELL, MARK, A, PENNING, THOMAS, D, YU, STELLA, S, RICO, JOSEPH, G
Format: Patent
Sprache:dan
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Beschreibung
Zusammenfassung:The present invention relates to a class of compounds represented by Formula Ior a pharmaceutically acceptable salt thereof, pharmaceutical composition comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the alphavbeta3 integrin.