Imidazolderivater som proteinkinase-inhibitorer, især EGF-R-tyrosinkinase

PCT No. PCT/EP95/04741 Sec. 371 Date Jun. 12, 1997 Sec. 102(e) Date Jun. 12, 1997 PCT Filed Dec. 1, 1995 PCT Pub. No. WO96/18626 PCT Pub. Date Jun. 20, 1996This invention relates to novel imidazole derivatives of formula a and pharmaceutically acceptable salts of these compounds, wherein R1, R2, R3,...

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Hauptverfasser:	KRASSO, ANNA, KAMBER, MARKUS, PIRSON, WOLFANG, WYSS, PIERREARLES, HARMON, CHARLES, STANFORD
Format:	Patent
Sprache:	dan
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	PCT No. PCT/EP95/04741 Sec. 371 Date Jun. 12, 1997 Sec. 102(e) Date Jun. 12, 1997 PCT Filed Dec. 1, 1995 PCT Pub. No. WO96/18626 PCT Pub. Date Jun. 20, 1996This invention relates to novel imidazole derivatives of formula a and pharmaceutically acceptable salts of these compounds, wherein R1, R2, R3, R5, R7 and R8 are as disclosed herein. These compounds are protein kinase inhibitors useful in the treatment of atherosclerosis, psoriasis, alopecia, and tumors.