Racemisering af forstadier for levobupivacain og analoge forstadier heraf

A process for the preparation of optically-enriched pipecolic acid as a salt with an optically-active acid, comprises asymmetric transformation of pipecolic acid, as a racemic mixture or a mixture enriched in the opposite enantiomer from that desired, with the optically-active acid in a solvent comp...

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Hauptverfasser: DYER, ULRICH, CONRAD, MCCAGUE, RAYMOND, WOODS, MARTIN
Format: Patent
Sprache:dan
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Zusammenfassung:A process for the preparation of optically-enriched pipecolic acid as a salt with an optically-active acid, comprises asymmetric transformation of pipecolic acid, as a racemic mixture or a mixture enriched in the opposite enantiomer from that desired, with the optically-active acid in a solvent comprising an acid that causes racemisation, in the absence of aldehyde. 00000