Arylalkyl-thiadiazinoner

3-Arylalkyl-5-phenyl-3,6-dihydro-1,3,4-thiadiazin-2-one derivs. of formula (I) and their salts and enantiomers are new. R1, R2 = H or A; R3, R4 = OH, OR10, SR10, SOR10, SO2R10, Hal, methylenedioxy, NO2, NH2, NHR10 or NR10R11; R5 = phenyl opt. mono- or disubstd. by R6 and/or R7; Q = direct bond or 1-...

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Hauptverfasser:	JONAS, ROCHUS, KLOCKOW, MICHAEL, WOLF, MICHAEL
Format:	Patent
Sprache:	dan
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	3-Arylalkyl-5-phenyl-3,6-dihydro-1,3,4-thiadiazin-2-one derivs. of formula (I) and their salts and enantiomers are new. R1, R2 = H or A; R3, R4 = OH, OR10, SR10, SOR10, SO2R10, Hal, methylenedioxy, NO2, NH2, NHR10 or NR10R11; R5 = phenyl opt. mono- or disubstd. by R6 and/or R7; Q = direct bond or 1-6C alkylene; R6, R7 = NH2, NR8R9, NHR10, NR10R11, NO2, Hal, CN, OA, COOH or COOA; R8, R9 = H; 1-8C acyl opt. substd. by 1-5 F and/or Cl; COOA; SA; SOA; SO2A; CONH2; CONHA; CONA2; COCOOH; COCOOA; COCONH2; COCONHA; or COCONA2; A = 1-6C alkyl opt. substd. by 1-5 F and/or Cl; R10, R11 = A, 3-7C cycloalkyl, 4-8C methylene-cycloalkyl or 2-8C alkenyl; Hal = F, Cl, Br or I.