Fremgangsmåde til rekombinant fremstilling af proteiner i gæren Hansenula

PCT No. PCT/EP94/02897 Sec. 371 Date Mar. 1, 1996 Sec. 102(e) Date Mar. 1, 1996 PCT Filed Sep. 1, 1994 PCT Pub. No. WO95/07356 PCT Pub. Date Mar. 16, 1995A process for the recombinant production of proteins in the yeast Hansenula comprises transforming Hansenula with an expression cassette which com...

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Hauptverfasser: SCHWEDEN, JUERGEN, STRASSER, ALEXANDER W.M, BOLLSCHWEILER, CLAUS, PIONTEK, MICHAEL, JANOWICZ, ZBIGNIEW A, WEYDEMANN, ULRIKE
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Zusammenfassung:PCT No. PCT/EP94/02897 Sec. 371 Date Mar. 1, 1996 Sec. 102(e) Date Mar. 1, 1996 PCT Filed Sep. 1, 1994 PCT Pub. No. WO95/07356 PCT Pub. Date Mar. 16, 1995A process for the recombinant production of proteins in the yeast Hansenula comprises transforming Hansenula with an expression cassette which comprises the following structural elements encoded: L-A-P-GEN where L is a leader sequence, A is an adaptor producing an alpha-helix structure, P is a processing signal and GEN is a structural gene for the required protein.