Detektion, assay og isolering af forbindelser med taxanringskelettet

The invention relates to a process for the determination and isolation from any source, either vegetable or biotechnological, of taxol and 10-deacetylbaccatin III (DAB) and their analogues using polyclonal IgY antibodies prepared from egg yolk from hens previously immunized with succinyl-taxol and s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BOMBARDELLI, EZIO, VENANZI, FRANCO M, CONCETTI, ANTONIO
Format: Patent
Sprache:dan
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Beschreibung
Zusammenfassung:The invention relates to a process for the determination and isolation from any source, either vegetable or biotechnological, of taxol and 10-deacetylbaccatin III (DAB) and their analogues using polyclonal IgY antibodies prepared from egg yolk from hens previously immunized with succinyl-taxol and succinyl-DAB conjugated with bovine albumin. These antibodies are immobilized on a matrix for selective isolation of the above taxanes from vegetable extracts or cell or microorganism culture media.