Varianter af galdesalt-stimuleret lipase, DNA-molekyler, som koder for dem, samt transgene, ikke-humane pattedyr

The invention discloses nucleic acids encoding variant Bile Salt Stimulated Lipase (BSSL; EC 3.1.1.1). The encoded variant BSSL enzymes maintain catalytic activity but contain fewer glycosylation sites that full-length BSSL. This reduced glycosylation facilitates purification and characterization of...

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Hauptverfasser: LUNDBERG, LENNART, HERNELL, OLLE, EDLUND, MICHAEL, STROEMQVIST, MATS, TOERNELL, JAN, BLAECKBERG, LARS, HANSSON, LENNART
Format: Patent
Sprache:dan
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Zusammenfassung:The invention discloses nucleic acids encoding variant Bile Salt Stimulated Lipase (BSSL; EC 3.1.1.1). The encoded variant BSSL enzymes maintain catalytic activity but contain fewer glycosylation sites that full-length BSSL. This reduced glycosylation facilitates purification and characterization of recombinant BSSL proteins.