23-oxaderivater i D-vitaminserien, fremgangsmåde til fremstilling heraf, farmaceutiske præparater indeholdende disse derivater samt deres anvendelse som lægemidler

23-oxaderivater i D-vitaminserien, fremgangsmåde til fremstilling heraf, farmaceutiske præparater indeholdende disse derivater samt deres anvendelse som lægemidler

PCT No. PCT/EP92/00123 Sec. 371 Date Jul. 19, 1993 Sec. 102(e) Date Jul. 19, 1993 PCT Filed Jan. 20, 1992 PCT Pub. No. WO92/12963 PCT Pub. Date Aug. 6, 1992.23-Oxa-derivatives in the vitamin D series of formula I (I) are described in which R1, R2 and R4 independently of one another mean a hydrogen a...

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Bibliographische Detailangaben
Hauptverfasser: RACH, PETRA, HABEREY, MARTIN, STEINMEYER, ANDREAS, SCHWARZ, KATICA, KIRSCH, GERALD, THIEROFF-EKERDT, RUTH, NEEF, GUENTER
Format: Patent
Sprache:dan
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ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:PCT No. PCT/EP92/00123 Sec. 371 Date Jul. 19, 1993 Sec. 102(e) Date Jul. 19, 1993 PCT Filed Jan. 20, 1992 PCT Pub. No. WO92/12963 PCT Pub. Date Aug. 6, 1992.23-Oxa-derivatives in the vitamin D series of formula I (I) are described in which R1, R2 and R4 independently of one another mean a hydrogen atom or an acyl group with 1 to 9 carbon atoms, R3 each means a hydrogen atom or each a linear or branched alkyl group with 1 to 4 carbon atoms and X means an alkylene radical-(CH2)n- with n=1, 2, 3, and if n=1, R3 each cannot be a methyl or propyl group, as well as a process for their production. The compounds have proliferation-inhibiting and cell-differentiation effects and are suitable for the production of pharmaceutical agents.