Tygbar sammensætning til frigørelse af et lægemiddel

A non-aqueous, chewable composition for oral delivery of unpalatable drugs is provided. The composition contains the drug intimately dispersed or dissolved in a pharmaceutically-acceptable lipid that is solid at room temperatures. The composition also has a matrix that contains a granulating agent f...

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Bibliographische Detailangaben
Hauptverfasser: GEYER, ROBERT P, TULIANI, VINOD V
Format: Patent
Sprache:dan
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Beschreibung
Zusammenfassung:A non-aqueous, chewable composition for oral delivery of unpalatable drugs is provided. The composition contains the drug intimately dispersed or dissolved in a pharmaceutically-acceptable lipid that is solid at room temperatures. The composition also has a matrix that contains a granulating agent for the total composition and a rapid dispersal agent and optionally additives such as buffering agents, flavoring agents, surfactants, and the like. Methods for the preparation of the chewable compositions are also provided.