Substituerede biphenylpyridoner som angiotensin II-antagonister

Substituted biphenylpyridones of the general formula in which R , R , R , R , R and A have the stated meanings, and D is a radical of the formula in which R and R have the stated meanings, can be prepared by alkylation of pyridones on the nitrogen. The substituted biphenylpyridones are suitable as a...

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Hauptverfasser: HANKO, RUDOLF, MUELLER, ULRICH, DRESSEL, JUERGEN, PH. D, STASCH, JOHANNES-PETER, KAZDA, STANISLAV, DR, MUELLER-GLIEMANN, MATTHIAS, ZAISS, SIEGFRIED, FEY, PETER, KRAEMER, THOMAS, KNORR, ANDREAS, BEUCK, MARTIN, WOHLFEIL, STEFAN, HUEBSCH, WALTER
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creator HANKO, RUDOLF
MUELLER, ULRICH
DRESSEL, JUERGEN, PH. D
STASCH, JOHANNES-PETER
KAZDA, STANISLAV, DR
MUELLER-GLIEMANN, MATTHIAS
ZAISS, SIEGFRIED
FEY, PETER
KRAEMER, THOMAS
KNORR, ANDREAS
BEUCK, MARTIN
WOHLFEIL, STEFAN
HUEBSCH, WALTER
description Substituted biphenylpyridones of the general formula in which R , R , R , R , R and A have the stated meanings, and D is a radical of the formula in which R and R have the stated meanings, can be prepared by alkylation of pyridones on the nitrogen. The substituted biphenylpyridones are suitable as active ingredients in pharmaceutical compositions, especially in pharmaceutical compositions which lower blood pressure and have antiatherosclerotic effects.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Substituerede biphenylpyridoner som angiotensin II-antagonister
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