Substituerede biphenylpyridoner som angiotensin II-antagonister

Substituted biphenylpyridones of the general formula in which R , R , R , R , R and A have the stated meanings, and D is a radical of the formula in which R and R have the stated meanings, can be prepared by alkylation of pyridones on the nitrogen. The substituted biphenylpyridones are suitable as a...

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Hauptverfasser: HANKO, RUDOLF, MUELLER, ULRICH, DRESSEL, JUERGEN, PH. D, STASCH, JOHANNES-PETER, KAZDA, STANISLAV, DR, MUELLER-GLIEMANN, MATTHIAS, ZAISS, SIEGFRIED, FEY, PETER, KRAEMER, THOMAS, KNORR, ANDREAS, BEUCK, MARTIN, WOHLFEIL, STEFAN, HUEBSCH, WALTER
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Sprache:dan
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Zusammenfassung:Substituted biphenylpyridones of the general formula in which R , R , R , R , R and A have the stated meanings, and D is a radical of the formula in which R and R have the stated meanings, can be prepared by alkylation of pyridones on the nitrogen. The substituted biphenylpyridones are suitable as active ingredients in pharmaceutical compositions, especially in pharmaceutical compositions which lower blood pressure and have antiatherosclerotic effects.