Pyrimidinnukleosidderivater med anti-tumor-aktivitet, deres fremstilling og anvendelse

Compounds of formula (I): Äin which: R , R and R are the same or different and each represents a hydrogen atom, an optionally substituted alkanoyl group or an alkenylcarbonyl group, provided that at least one of R , R and R represents an unsubstituted alkanoyl group having from 5 to 24 carbon atoms,...

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Bibliographische Detailangaben
Hauptverfasser:	SHIBATA, TOMOYUKI, HOTODA, HITOSHI, KOBAYASHI, TOMOWO, MATSUDA, AKIRO, SASAKI, TAKUMA, KANEKO, MASAKATSU, MITSUHASHI, YOSHIHIRO
Format:	Patent
Sprache:	dan
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	Compounds of formula (I): Äin which: R , R and R are the same or different and each represents a hydrogen atom, an optionally substituted alkanoyl group or an alkenylcarbonyl group, provided that at least one of R , R and R represents an unsubstituted alkanoyl group having from 5 to 24 carbon atoms, said substituted alkanoyl group or said alkenylcarbonyl group; and one of R4 and R5 represents a hydrogen atom and the other represents a cyano groupÜ; have valuable anti-tumour activity.