Fremstilling af virusvaccine

Immunogenic envelope glycoproteins are produced from enveloped virus, such as of the paramyxoviridae family, particularly PIV-3 and RSV, by culturing the virus in the substantial absence of exogenous serum proteins, isolating the virus from the tissue culture, solubilizing the envelope glycoproteins...

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Bibliographische Detailangaben
Hauptverfasser: EWASYSHYN, MARY ELIZABETH, BONNEAU, ANNE-MARIE, KLEIN, MICHEL HENRI, CAPLAN, BARRY IAN
Format: Patent
Sprache:dan
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Zusammenfassung:Immunogenic envelope glycoproteins are produced from enveloped virus, such as of the paramyxoviridae family, particularly PIV-3 and RSV, by culturing the virus in the substantial absence of exogenous serum proteins, isolating the virus from the tissue culture, solubilizing the envelope glycoproteins and isolating the solubilized envelope glycoproteins by chromatography.