PHARMAZEUTISCHE FORMULIERUNGEN ENTHALTEND EIN 2[[(2-PYRIDINYL)METHYL]SULFINYL]BENZIMIDAZOL MIT ANTIULCUS WIRKUNG UND VERFAHREN ZUR HERSTELLUNG SOLCHER FORMULIERUNGEN

Oral pharmaceutical formulation comprising granules having an inert core coated with a layer, comprising a 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazole having anti-ulcer activity, a disintegrant and a surfactant in a matrix of a melt coating substance essentially consisting of one or more esters o...

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Hauptverfasser: KANN, HELLE, SOERENSEN, EICHSTEDT, PEDERSEN, BOLS, HENRIKSEN, LUND
Format: Patent
Sprache:ger
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Zusammenfassung:Oral pharmaceutical formulation comprising granules having an inert core coated with a layer, comprising a 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazole having anti-ulcer activity, a disintegrant and a surfactant in a matrix of a melt coating substance essentially consisting of one or more esters of glycerol and fatty acids, a separating layer and an enteric coating layer, and a process for the preparation of such formulation using a melt coating technique for the preparation of the benzimidazole containing layer.