POLYHYDROXYALKYLPYRAZINE DERIVATE,DEREN HERSTELLUNG UND DIESE ENTHALTENDE ARZNEIMITTELN

POLYHYDROXYALKYLPYRAZINE DERIVATE,DEREN HERSTELLUNG UND DIESE ENTHALTENDE ARZNEIMITTELN

The present invention relates to medicaments comprising at least one compound of formula:whereineither R1 represents a -CH(Ra)-CHOH-CHOH-CH2OH chain andR2 represents a -CH2-CHOH-CHOH-CH2OH chain,or R1 represents a -CHOH-CHF-CHOH-CH2OH chain and R2 represents a -CH2-CHF-CHOH-CH2OH chain,or R1 represe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BASHIARDES, GEORGES, FILOCHE, BRUNO, CARRY, JEANRISTOPHE, MIGNANI, SERGE, EVERS, MICHEL
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to medicaments comprising at least one compound of formula:whereineither R1 represents a -CH(Ra)-CHOH-CHOH-CH2OH chain andR2 represents a -CH2-CHOH-CHOH-CH2OH chain,or R1 represents a -CHOH-CHF-CHOH-CH2OH chain and R2 represents a -CH2-CHF-CHOH-CH2OH chain,or R1 represents a -CHOH-CHOH-CHOH-Rb chain and R2 represents a -CH2-CHOH-CHOH-Rb chain,or R1 represents a -CH2-CHOH-CHOH-CH2OH chain and R2 represents a -CH2-CHOH-CHOH-CH2OH chain,or R1 and R2 are identical and each represent a -(CHOH)n-CH2OH chain in which n is equal to 1, 2, 3 or 4,Ra represents an alkoxy radical (1-6 C in a straight or branched chain) or a fluorine atom, andRb represents a carboxyl, -CO-NH2 or -CH2-NH2 radical,or one of their stereoisomers or their salts with an inorganic or organic acid, to novel compounds of formula (I) and to their preparation.