Verwendung eines Rifamycin-Derivates zur Herstellung eines Medikamentes zur Behandlung von Krankheiten verursacht durch Helicobacter pylori-Infektionen

A curative medicine for a digestive organ disease caused by the infection of Helicobacter comprising as an effective component a rifamycin derivative expressed by the formula (I) or the formula (II), or a physiologically acceptable salt thereof. In the formula (I), X represents an oxygen atom or a s...

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Hauptverfasser: SAKASHITA, SHINICHI, YAMANE, TAKEHIKO, HOSOE, KAZUNORI, FUJII, KENJI, YAMASHITA, KATSUJI
Format: Patent
Sprache:ger
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Zusammenfassung:A curative medicine for a digestive organ disease caused by the infection of Helicobacter comprising as an effective component a rifamycin derivative expressed by the formula (I) or the formula (II), or a physiologically acceptable salt thereof. In the formula (I), X represents an oxygen atom or a sulfur atom, R represents an acetyl group or a hydrogen atom, R represents a hydroxy group or a hydrogen atom, R represents Äin which R and R are the same or different and each is an alkyl group having 1 to 3 carbon atoms or a group expressed by the formula (in which m represents an integer between 1 and 3)Ü, or Äin which R and R are the same or different and each is a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, X represents an oxygen atom or a sulfur atom or NR äR represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms or -(CH2)nX (in which n represents an integer between 1 and 4, and X represents an alkoxy group having of 1 to 3 carbon atoms, or a vinyl group or an ethynyl group, or a group expressed by the formula In the formula (II), R represents an alkyl group having 1 to 7 carbon atoms.