FANGVERFAHREN UND TESTMETHODEN

Methods of capturing and labelling a species, comprise attracting magnetically attractable particles to a solid support by magnetic forces, which particles have an affinity for said species, contacting said particles on said support with a sample containing said species to capture said species onto...

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1. Verfasser: PARTON, ADRIAN
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:Methods of capturing and labelling a species, comprise attracting magnetically attractable particles to a solid support by magnetic forces, which particles have an affinity for said species, contacting said particles on said support with a sample containing said species to capture said species onto said particles on said support, and binding said species captured on said particles directly or indirectly to a detectable label before and/or whilst said species is captured on said particles on said support. The label may be bound to said captured species via an immunological binding partner which binds selectively to said species and may be a fluorescent label, luminescent label, enzyme label, dye label, phosphorescent label, metal-chelating label, radio label, spin label, heavy metal label, nucleic acid or nucleic acid analogue hybridisation label, avidin or avidin-like label suitably bound to or incorporated in particles which also bear a binding agent such as an antibody causing said particles to bind to the said captured species.